Master’s Thesis – Ion Release and Implant Materials: The Effect of Surface Topography and Nanocoatings
[APPLICATION CLOSED]
Titanium and cobalt-chrome are frequently used as implant materials in dentistry and orthopedics. Ion release from the implant to the surrounding tissue after implantation always occur, and normally does not create any adverse effects if the amounts are low. In some cases, the ion release may be greatly increased, for example when wear debris detaches from the implant, or if bacteria start to grow on the implant surface. Recent studies highlight a correlation between metal ion release and inflammatory responses, which may hamper the bone regeneration and implant integration.
Aim
This thesis will be investigating the relationship between surface topography and ion release from common implant materials, such as titanium and cobalt-chrome. Additionally, we will explore the potential impact of nanocoatings on the ion release.
We are looking for a candidate…
- With a background in Chemistry and/or Chemical Engineering
- Who learns fast, can work independently, is motivated and a team-player
- With fluency in English
- Who is proficient in Microsoft Word and Excel
- With previous lab work experience
Who are we?
Promimic’s nanotechnology, HAnano Surface, creates a unique bioactive surface on any implant. The HAnano Surface has demonstrated faster and stronger osseointegration in over 30 clinical studies, with over 1.4 million clinical applications to date.
The HAnano Surface is a 20 nanometer thin implant surface treatment composed of crystalline hydroxyapatite (HA) particles, which have the same shape, composition, and structure as HA found in human bone.
We are located in GoCo Health Innovation City in Mölndal, easily accessible by car, bike or bus from Gothenburg.
What can we offer?
Promimic offers a hands-on research opportunity in the field of nano-surface technologies and material surfaces. As part of our team, students can contribute to cutting-edge projects that focus on enhancing the performance of medical implants. This involves applying theoretical knowledge to develop innovative solutions, with access to specialized labs, equipment, and resources not typically found in academic settings. Our experienced professionals provide mentorship, guiding students as they explore the complexities of ion release from titanium and cobalt chrome implants. This thesis investigates the relationship between surface roughness and ion release, incorporating analytical methods such as Scanning Electron Microscopy (SEM), Energy-Dispersive X-ray Spectroscopy (EDX), and Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP-AES). It’s a chance to contribute meaningfully to healthcare advancements while gaining practical experience in a real-world application. Compensation is included.
Start: January 2024Duration: 20 weeks
Please send your application to per.kjellin@promimic.mkdev.nu